Neuroscience
| 2 min read
The first proof-of-concept study showed that the gene therapy reduced the production of cerebrospinal fluid in the brains of mice.
| 6 min read
Alzheimer’s disease often overlaps with other causes of cognitive decline. A new proteomics project aims to untangle that mixture and help researchers identify the right patients for future clinical trials.
| 3 min read
Scientists identified stem cells whose dysregulated calcium signaling drives the degenerative condition, opening the door to novel treatments.
| 2 min read
In mice, the new drug led to recovery of motor function and vision by protecting nerve fibers and myelin.
| 2 min read
Patients often show symptoms about ten years earlier than usual. The new work pinpointed a genetic variant that makes it happen.
| 4 min read
Whole-exome sequencing identified 36 genes associated with OCD and chronic tic disorders, expanding researchers’ understanding of the biology underlying both conditions.
| 3 min read
The novel stem-cell derived retinal organoid provided a new understanding of the disease by showing that damage to retinal pigment epithelium cells is enough to cause neurodegeneration of photoreceptors.
| 4 min read
Neuro-Innovators is testing whether a combination of existing medicines can promote neuroplasticity and improve outcomes for people living with chronic stroke disability.
| 4 min read
Multimodal approaches could help drug developers connect disease biology with clinical outcomes and better understand why treatments succeed or fail.
| 5 min read
Rodrigo Cristofoletti discusses how cerebral organoids, advanced imaging, and quantitative modeling are helping researchers better understand brain development, disease, and drug discovery.
| 6 min read
A new AI analysis of a negative Alzheimer's trial raises questions about whether conventional clinical trials are missing patients who could still benefit from treatment.
| 4 min read
As non-opioid pain therapies continue to face setbacks, Insilico is using AI to uncover new biology and therapeutic targets.
