Neuroscience
| 6 min read
QurAlis researchers have developed QRL-101, a new drug candidate that targets overactive neurons to prevent cell death in ALS. 
| 4 min read
Biotech and pharma leaders reveal the neurological therapies in development that they’re most excited about.
| 3 min read
A statistical model using two measures of brain activity could anticipate if people given an injection would be in severe pain for the next month.
| 4 min read
In a Phase 2b trial, Khondrion’s sonlicromanol led to significant health benefits for patients with mitochondrial disease linked to a common mutation.
| 3 min read
A gene therapy targeting organs beyond the brain could improve quality of life and possibly extend survival in children with the neurodegenerative disease.
| 3 min read
Unlike in other brain regions, levels of the neurotransmitter decrease in the cerebellum when anxiety is high, suggesting a potential new drug target.
| 3 min read
Vertex Pharmaceuticals’ drug, Journavx, blocks a sodium channel outside of the brain. Experts hope that this non-addictive pain drug may be the first of many.
| 4 min read
People and mice with ALS-linked mutations show altered sleep patterns early in life. Modifying sleep hormone levels normalized sleep cycles in mice.
| 3 min read
Levels of neuroactive steroids during the third trimester of pregnancy may indicate postpartum depression risk.
| 4 min read
Targeting a gut bacterial species or its metabolites could potentially improve diabetes management by reducing sugar preferences.
| 8 min read
Lundbeck Therapeutics is testing a monoclonal antibody that targets a novel neuropeptide in a Phase 2b clinical trial.
| 4 min read
The protein APLP1 strongly associates with brain-derived EVs. A blood test could one day isolate these molecular packets to diagnose neurological disorders.
| 3 min read
The gene therapy treats the rare genetic disease AADC deficiency by delivering a functional gene into the brain.
| 3 min read
Researchers developed a new pill with promising applications for treating pain due to gastrointestinal disorders.
| 5 min read
Industry leaders predict the most exciting advances in drug discovery and development in the coming year.
| 4 min read
Genetic analysis of organoids and brain tumors showed that the cancers are packed with cells that haven’t reached a mature state.
| 3 min read
An oligonucleotide transport vehicle could transform neurological disease treatment by enhancing drug delivery across the blood-brain barrier.
| 3 min read
The FDA approved two new medications for Niemann-Pick disease type C that improve symptoms, showing the power of community advocacy.
| 3 min read
New research revealed that manufacturer-funded clinical trials deem drugs more effective than non-sponsored trials.
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Explore the role and cellular mechanisms of neuroinflammation in Parkinson’s disease.
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Understanding neuroinflammation in Parkinson's disease
Explore the role and cellular mechanisms of neuroinflammation in Parkinson’s disease.
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