While amyloid plaques form first, new work suggests targeting tau tangles that spread through the brain could also help the fight against this devastating disease.
For the first time, researchers observed new conformational states between opioid drugs binding to mu opioid receptors — findings that drug developers can use to design safer opioid drugs.
Award-winner Cheng Lyu shows how tiny changes in circuit wiring can shift an animal’s behavior, illuminating the developmental rules of the nervous system.
Acquisition brings Avidity’s RNA delivery platform and late-stage neuromuscular programs under Novartis, expanding its capabilities in developing precision genetic medicines.