DDN Weekly Rundown text on a blue backgroundRegulatory & Industry
| 4 min read
A win for autoimmune disease, a set back for Alzheimer’s disease, an FDA backing for a multi-cancer blood test, and more led the news this week.
 Give me alt text for this image: Illustration of three dark navy silhouetted hands editing strands of DNA against an abstract painted background in dusty pink, rust, gray, and teal. One hand holds scissors cutting a double helix, while two others use tweezers to lift and reposition a cut strand. Smaller DNA fragments float throughout the scene, suggesting gene editing.Tools & Techniques
| 3 min read
Autonomous agents flagged a family of phage enzymes with CRISPR-like repeats, though what the system does remains unknown.
A female doctor analyzing brain scans.Cancer
| 4 min read
Proteogenomic analysis of brain tumors identified potential treatment targets and prognostic markers that differed across age, developmental stage, and sex.
T cells attacking a cancer cell on a blue backgroundCancer
| 3 min read
The new highly scalable therapy successfully slowed tumor growth in mouse models of solid tumors.
A back view of a crowded conference room with a large projector showing a science talk. Regulatory & Industry
| 5 min read
From computationally designed repertoires to AI-driven specificity prediction and multispecific therapeutics, antibody researchers are developing new ways to design molecules for the biology they need to influence.

News

A brain with DNA and synapse imagery.
| 4 min read
DDN Weekly Rundown text in blue and white
| 3 min read
A pink ceramic brain with blue cracks on a gray background
| 2 min read
A snake coiled on a branch, symbolizing themes in recombinant antivenom development.
| 3 min read
DDN Weekly Rundown text on a blue background
| 4 min read
Blue-stained cells under microscope, illustrating molecular glue degraders
| 3 min read

Cancer Research News

Molecular illustration of the amivantamab EGFR-MET bispecific antibody mechanism in EGFR exon 20 insertion NSCLC, showing simultaneous receptor binding, immune effector cell recruitment via the Fc region, and receptor internalization through membrane invagination.
Final PAPILLON data show amivantamab-vmjw plus chemotherapy reaches 34 months median OS, the longest reported in this historically treatment-resistant NSCLC subtype
Three people getting blood transfusions at the hospital.
CAR T has transformed treatment for some blood cancers, but manufacturing and healthcare system constraints still prevent many eligible patients from receiving it.

Editor's Pick

An illustration of cells with orange nuclei and transparent cytoplasm
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.
An illustration of bone marrow containing immune and hematopoietic stem cells
In a journey fraught with heartache and persistence, medical research giants paved the way for successful bone marrow transplantation. 

Multimedia

Crystal Girod, Senior Product Manager at Beckman Coulter Life Sciences, featured in a “Tell Us What You Know” graphic titled “Making Lab Automation More Accessible,” alongside the Beckman Coulter Life Sciences logo.
Explore how advances in liquid handling are making automation more accessible, flexible, and practical for modern labs.
3D illustration of an antibody-drug conjugate with cytotoxic payloads attached to an antibody.
Explore how integrated cell-based assays reveal the mechanisms that drive antibody-drug conjugate activity and inform candidate selection.
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Crystal Girod, Senior Product Manager at Beckman Coulter Life Sciences, featured in a “Tell Us What You Know” graphic titled “Making Lab Automation More Accessible,” alongside the Beckman Coulter Life Sciences logo.
Explore how advances in liquid handling are making automation more accessible, flexible, and practical for modern labs.
Puzzle pieces spelling “DATA” alongside connected icons representing data analysis, storage, and reporting.
Earlier insight into analytical data can help laboratories recognize emerging trends and maintain method performance over time.
3D illustration of an antibody-drug conjugate with cytotoxic payloads attached to an antibody.
Explore how integrated cell-based assays reveal the mechanisms that drive antibody-drug conjugate activity and inform candidate selection.