A microscope surrounded by separate groups of diverse people. Tools & Techniques
| 3 min read
Growing evidence supports the use of virtual controls in toxicology, but their broader adoption will depend on rigorous data curation, pathology expertise, and robust validation.
Weekly Rundown imageRegulatory & Industry
| 5 min read
Clinical trial updates, regulatory approvals, and more led the news this week.
Human brain puzzle with a few missing pieces.Neuroscience
| 4 min read
BCG vaccination reduced tau pathology and neuroinflammation in mice, prompting researchers to investigate whether trained immunity could inform future treatments for Alzheimer’s disease.
A microscopic image of blue-colored bacteriaCancer
| 3 min read
Bacterial genomes recovered from discarded DNA sequencing data could help researchers investigate whether microbes contribute to aggressive prostate cancer.
The formation and processing of RNA from DNA.Internal Medicine
| 4 min read
A machine learning-based screen identified SRSF1 as a potential target for reversing several hallmarks of aging without erasing cell identity, with further testing revealing benefits in aged mice.

News

DDN Weekly Rundown text in blue and white on a blue background
| 4 min read
A brain scan with an enlarged ventricle shown on a computer screen
| 2 min read
A needle inserted into a vaccine bottle with a DNA helix inside
| 2 min read
cellular display
| 3 min read
DDN Weekly Rundown blue text on a white and blue background
| 4 min read
A blue glove holding a vial full of plasma and blood
| 6 min read

Cancer Research News

Scientific illustration of two chromosomes fusing at a teal-glowing breakpoint in a leukemia cell, with a gold RNA strand emerging from the junction against a dark navy sequencing data background.
OGT's first dedicated fusion MRD NGS panel targets the roughly one-quarter of AML cases where RNA fusion transcripts, not DNA mutations, define residual disease
Two pink cancer cells dividing on a blue background
Researchers showed that before cancer cells metastasize the brain, they enter a “proliferative pause” that can be targeted with drugs to prevent metastasis altogether.

Editor's Pick

An illustration of cells with orange nuclei and transparent cytoplasm
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.
An illustration of bone marrow containing immune and hematopoietic stem cells
In a journey fraught with heartache and persistence, medical research giants paved the way for successful bone marrow transplantation. 

Multimedia

Researcher examining a multiwell plate alongside cell culture dishes in a laboratory.
Explore how direct cell lysis can reduce sample preparation steps and support efficient gene expression analysis by RT-qPCR.
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Scientists in a laboratory conducting pharmaceutical research using laboratory equipment and analytical instruments.
Explore a strategic guide to IND-enabling nonclinical development for small molecules and biologics.
Digital illustration of a human brain composed of glowing neural connections, surrounded by colorful, blurred lights against a dark blue background.
Discover how researchers are looking beyond individual neurons to understand how genetic variations shape activity across brain organoid networks.
3D illustration of a Y-shaped antibody with pink and blue molecular structures against a blurred pink and purple background.
Explore how dual binding assays reveal interactions between bispecific antibodies and their targets, providing insights into binding behavior and antibody function.