DDN Weekly Rundown in blue text on a blue and white backgroundRegulatory & Industry
| 4 min read
Two new FDA approvals, a CRISPR program discontinued, discussions of a major merger, and more led the news this week.
A purple microscopic photo of melanoma cancer cellsCancer
| 2 min read
A new alternative approach to antibody-drug conjugates takes advantage of cancer cells’ need for fuel — first by encouraging them to overdose on glucose and then by blocking its backup source of fat.
A hand holding four packets of colorful antibiotic pillsInfectious Disease & Vaccines
| 2 min read
A new study showed environmental bacteria can transfer resistance genes to pathogens inside human lungs that were previously sensitive to antibiotics. The findings could prompt new treatments that block the gene transfer.
Brain in a protective dome against a blue background. Neuroscience
| 5 min read
Montara Therapeutics is taking a different approach to CNS drug development by using the blood-brain barrier to restrict drug activity outside the brain and reduce dose-limiting toxicities.
A detailed 3D image of cells alongside a DNA helix structure. Rare & Genetic Diseases
| 3 min read
Analysis of two pivotal Yescarta clinical trials revealed that patients' germline DNA influences both toxicity risk and CAR T expansion, opening new opportunities for smarter cell therapy design.

News

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| 4 min read
Single strand ribonucleic acid.
| 5 min read
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| 4 min read
Business partners shaking hands in a modern office
| 3 min read
A bright blue brain with a blue DNA helix
| 3 min read
Argenx company logo on building exterior
| 2 min read

Cancer Research News

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Phase Advance is using mechanistic virtual patient models to predict how LEAF4Life's hypoxia-targeting therapy could perform across multiple indications.
A 3D medical illustration of a cancer cell or tumor, featuring a main red mass covered in bumpy white textures with long, root-like tentacles branching outward across a gray surface.
Learn how patient-derived tumor organoids, AI, and phenotypic screening are advancing the discovery of small molecule therapeutics.

Editor's Pick

An illustration of cells with orange nuclei and transparent cytoplasm
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.
An illustration of bone marrow containing immune and hematopoietic stem cells
In a journey fraught with heartache and persistence, medical research giants paved the way for successful bone marrow transplantation. 

Multimedia

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Discover practical strategies to improve pipetting accuracy, reproducibility, ergonomics, and instrument performance across diverse laboratory workflows.
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Learn how developmental and reproductive toxicology study selection supports regulatory decision-making and generates meaningful nonclinical safety data.
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