DDN Weekly Rundown text written in blue on a blue and white backgroundRegulatory & Industry
| 4 min read
FDA guidance, trial results, glioblastoma studies, and more led the news this week.
A brightly colored abstract representation of complex pathways or neural connections. Rare & Genetic Diseases
| 3 min read
A new approach to protein degradation improved mitochondrial function and neuronal survival in cell models of several mitochondrial disorders.
A chromosome with a deletion is shown on a blue backgroundRare & Genetic Diseases
| 2 min read
Researchers tested a new antisense oligonucleotide therapy that turns the maternal healthy genes back on to target the underlying cause of disease.
A female technician doing an MRI scan of a patient’s brain. Metabolic Disease
| 4 min read
Researchers ​are beginning to uncover differences in brain metabolism and cognitive performance among people with PMOS, but it’s still unknown what drives these changes and whether they have long-term consequences.
A microscopic view of pancreatic ductal adenocaricoma.Cancer
| 2 min read
The multi-omics data on nearly half a million tumor cells showed that even cells with almost identical genetic makeup can show radically different behavior.

News

Weekly Rundown image
| 5 min read
Human brain puzzle with a few missing pieces.
| 4 min read
A microscopic image of blue-colored bacteria
| 3 min read
The formation and processing of RNA from DNA.
| 4 min read
DDN Weekly Rundown text in blue and white on a blue background
| 4 min read
A brain scan with an enlarged ventricle shown on a computer screen
| 2 min read

Cancer Research News

Scientific illustration of two chromosomes fusing at a teal-glowing breakpoint in a leukemia cell, with a gold RNA strand emerging from the junction against a dark navy sequencing data background.
OGT's first dedicated fusion MRD NGS panel targets the roughly one-quarter of AML cases where RNA fusion transcripts, not DNA mutations, define residual disease
Two pink cancer cells dividing on a blue background
Researchers showed that before cancer cells metastasize the brain, they enter a “proliferative pause” that can be targeted with drugs to prevent metastasis altogether.

Editor's Pick

An illustration of cells with orange nuclei and transparent cytoplasm
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.
An illustration of bone marrow containing immune and hematopoietic stem cells
In a journey fraught with heartache and persistence, medical research giants paved the way for successful bone marrow transplantation. 

Multimedia

Colorful stylized DNA double helix strands against a dark background.
Explore how enzymatic DNA synthesis can support longer, more complex constructs for genome editing, mRNA, and synthetic biology workflows.
Researcher examining a multiwell plate alongside cell culture dishes in a laboratory.
Explore how direct cell lysis can reduce sample preparation steps and support efficient gene expression analysis by RT-qPCR.
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Explore how enzymatic DNA synthesis can support longer, more complex constructs for genome editing, mRNA, and synthetic biology workflows.
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Explore a strategic guide to IND-enabling nonclinical development for small molecules and biologics.
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Discover how researchers are looking beyond individual neurons to understand how genetic variations shape activity across brain organoid networks.