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Three Schistosoma worms moving in circles.

A single enzyme targets a parasite’s weak spot

A single enzyme targets a parasite’s weak spot

Inhibitors of an enzyme essential for schistosomiasis parasitic infection effectively combat the condition in mice.
Mouse approaching a small bottle of yellowish liquid.

From mice to men: breaking the transmission cycle of Lyme disease

From mice to men: breaking the transmission cycle of Lyme disease

Last year, the USDA conditionally approved an oral vaccine for mice to reduce the transmission of Lyme disease to humans.
A 3D rendering of voltage-gated sodium channel Nav1.7 (shown as a blue blob structure) embedded into a membrane next to regulatory protein CRMP (shown as a ribbon diagram encased within a yellow blob). A yellow region within the Nav1.7 structure signifies the CRMP binding site.

A gene therapy for chronic pain

A gene therapy for chronic pain

Researchers identified a peptide that selectively blocks pain signaling in sensory neurons and packaged it into a viral-based gene therapy in a step towards treating chronic pain without the risk for addiction.
Mitochondria.

A touch of toxic gas could power health

A touch of toxic gas could power health

Although harmful in large quantities, hydrogen sulfide may ameliorate the health consequences of aging when small doses are applied to the mitochondria.
A white macrophage engulfs bright red bacteria against a dark red background.

Correcting for tuberculosis susceptibility

Correcting for tuberculosis susceptibility

Using a machine learning approach, researchers discovered how to make mouse macrophages resistant to tuberculosis infection.
A 3D rendering of myelinated neurons transmitting impulses on a black background.

A novel candidate drug improves multiple sclerosis signs in mice

A novel candidate drug improves multiple sclerosis signs in mice

An allosteric inhibitor may block glutamate’s toxic effects in the brain without affecting healthy synaptic neurotransmission.
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