| 7 min read
CAR T has transformed treatment for some blood cancers, but manufacturing and healthcare system constraints still prevent many eligible patients from receiving it.
| 5 min read
From computationally designed repertoires to AI-driven specificity prediction and multispecific therapeutics, antibody researchers are developing new ways to design molecules for the biology they need to influence.
| 4 min read
Researchers are developing new delivery technologies to bring gene therapies to the central nervous system safely and precisely.
| 3 min read
New partnerships, an expedited IND program from the FDA, another Phase 3 win for a LSD-based anxiety drug, and more led the news this week.
| 2 min read
Patients often show symptoms about ten years earlier than usual. The new work pinpointed a genetic variant that makes it happen.News
| 3 min read
A recombinant antivenom made of five nanobodies protected mice against lethal doses of venom from four medically important snake species in India.
| 4 min read
A failed RNA drug, major job cuts, a win for myeloma CAR T, and more led the news this week.
| 3 min read
Starting from a defined mechanism can cause discovery programs to miss the best drug candidates.
| 3 min read
Researchers at Erasmus MC and Apeximmune independently identified PLA2G2D as a potential new target for restoring antitumor T cell responses.
| 7 min read
This year’s awardees were recognized for their achievements in the discovery of orexin, the development of a novel bispecific antibody, and bringing patients to the forefront of drug discovery.
| 4 min read
Whole-exome sequencing identified 36 genes associated with OCD and chronic tic disorders, expanding researchers’ understanding of the biology underlying both conditions.
Cancer Research News
Final PAPILLON data show amivantamab-vmjw plus chemotherapy reaches 34 months median OS, the longest reported in this historically treatment-resistant NSCLC subtype
Transgene expands a duck-cell-line license as its personalized cancer vaccines advance deeper into the clinic
Editor's Pick
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.
In a journey fraught with heartache and persistence, medical research giants paved the way for successful bone marrow transplantation.
Multimedia
Explore how advances in liquid handling are making automation more accessible, flexible, and practical for modern labs.
Explore how integrated cell-based assays reveal the mechanisms that drive antibody-drug conjugate activity and inform candidate selection.
