A scientist with a blue-gloved hand holds a beaker with psilocybin mushrooms and faded colors on top.Neuroscience
| 3 min read
Despite using identical protocols, the group of researchers showed that many oft-reported positive effects of psilocybin were not reproducible.
DDN Weekly Rundown text in blue on a blue and white backgroundRegulatory & Industry
| 4 min read
Psychedelic therapy updates, a novel application for bone marrow, and a hefty price tag for a priority review voucher led the news this week.
Colorful DNA strands on black background. Regulatory & Industry
| 3 min read
Big Pharma spent billions on in vivo delivery, gene insertion, and engineered capsids, while a late-stage Fabry disease program found a new owner.
3D rendering of cells and DNA on a blue background. Tools & Techniques
| 3 min read
A laser-guided nanoneedle approach brings genetic delivery down to the level of individual cells, opening new possibilities for studying how altered cells influence their surroundings.
A lab hallway with computing equipment on the left and white lines on a black wall to the right.Regulatory & Industry
| 5 min read
No VAV1 drug has reached approval, and four are now in development. Insilico’s AI-designed degrader makes its case on where the molecule does not go.

News

DDN Weekly Rundown text in blue and white on a dark blue background
| 4 min read
Digital composite of a sperm and egg.
| 4 min read
A microscopic rendering of circular plasmid DNA on a black background
| 3 min read
Silhouette of the liver lined with pills on a blue background.
| 4 min read
A man wearing an EEG headset in front of a monitor screen.
| 5 min read
Anatomical representation of a 3D heart.
| 4 min read

Cancer Research News

Fluorescence microscopy of blue DAPI-stained interphase nuclei with paired red and green FISH probe signals detecting IGH translocations in hematological malignancy.
IVDR-certified CytoCell probes for IGH and ATM extend FISH in CLL and myeloma, filling gaps where sequencing turnaround and structural detection fall short
A microscopic view of pancreatic ductal adenocaricoma.
The multi-omics data on nearly half a million tumor cells showed that even cells with almost identical genetic makeup can show radically different behavior.

Editor's Pick

An illustration of cells with orange nuclei and transparent cytoplasm
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.
An illustration of bone marrow containing immune and hematopoietic stem cells
In a journey fraught with heartache and persistence, medical research giants paved the way for successful bone marrow transplantation. 

Multimedia

Molecular illustration of several antibodies binding to a protein target.
Explore how surface plasmon resonance can reveal binding kinetics, epitope relationships, and receptor interactions to guide antibody lead optimization.
Colorful stylized DNA double helix strands against a dark background.
Explore how enzymatic DNA synthesis can support longer, more complex constructs for genome editing, mRNA, and synthetic biology workflows.
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Gloved hand holding a multiwell cell culture plate under a fluorescence microscope for spheroid analysis.
Using confocal live-cell imaging to characterize immune-mediated cytotoxicity over time.
Fluorescence microscopy image of cells displaying green and red fluorescent signals.
Using confocal live-cell imaging to assess treatment effects in spheroids, organoids, and co-cultures.
3D illustration of Y-shaped antibody molecules floating against a soft blue background, with a detailed antibody structure in the foreground.
From molecular developability to functional activity, integrated characterization strategies help inform lead selection and optimization in biologics discovery.