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A photograph of Segun Fatumo and his colleague wearing white lab coats and working in a laboratory.

Sequencing 100,000 genomes to revolutionize Nigerian genomics

Sequencing 100,000 genomes to revolutionize Nigerian genomics

With diseases like cancer and kidney disease on the rise in Africa, Segun Fatumo and his team are sequencing the genomes of 100,000 Nigerians to understand why.
A woman in a pink shirt sits on an examination table and talks to a doctor wearing a white coat and stethoscope.

Addressing sex differences in autoimmune diseases

Addressing sex differences in autoimmune diseases

Susan Kovats explores the role of sex hormones in autoimmunity to guide the development of therapeutics for lupus, Sjögren’s syndrome, and other diseases that preferentially affect women.
Green-colored axonal projections from neurons with blue-colored nucelli flank a central oblong blue shape, creating a butterfly-like look.

Sociable circuits

Sociable circuits

A neural circuit responsible for the social reward response unravels the mystery of what drives human sociality.
A photo of bottles of frozen breast milk standing in a freezer.

For neurological disorders, milk-based therapies are on the way

For neurological disorders, milk-based therapies are on the way

From peptides to sugars to lipids, researchers investigate milk as an untapped source of therapeutics for conditions as diverse as anxiety and infant brain injury.
Hands held up to a screen displaying hexagons containing pills, a doctor, a map, and other drug discovery scenes.

A new database helps predict effective drug combinations

A new database helps predict effective drug combinations

Researchers developed a continuously updated database to help computational models screen combinatorial drugs for evasive diseases.
A 3D-rendered image of neurons firing.

Manipulating nerves to relieve pain without drugs

Manipulating nerves to relieve pain without drugs

Seeking alternatives to pharmacological approaches, researchers apply thermal, electrical, and mechanical stimuli to change nerve signaling and treat pain.
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November 2022 Issue Front Cover

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• Volume 18 • Issue 11 • November 2022

November 2022

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