Metabolic Disease

Sagimet’s denifanstat delivered significant improvements in disease activity and fibrosis for patients with metabolic dysfunction-associated steatohepatitis.

Injectable micelles that release glucagon could provide a new way to treat hypoglycemic events in diabetes.

Customizable hydrogels could make taking diabetes and cancer medications as well as other biologics easier for patients.

AMSBIO has launched a glucagon-like peptide 1 receptor (GLP-1R) reporter cell line.

Specialized cells in omental adipose tissue may repress fat cell development.

Paolo Martini leads the biotech company’s rare disease research program with the hope of developing the very first treatments for genetic metabolic disorders.

With some out-of-the-box engineering, researchers have developed a nature-inspired strategy to turn sugar in packaged foods into gut-healthy fiber.

Scientists have appreciated the roles of bacteria in our microbiomes for decades. Now, they’re studying the effects of the trillions of viruses that call the human body home.

High resolution microscopy revealed distinct mitochondrial populations in inner ear hair cells, setting the stage for probing their role in mitochondrial deafness.

A new oral bead technology is designed to stimulate nutrient-sensing cells in discrete parts of the gut to restore metabolic balance.

Mitchell Lazar studies the transcription factors linking circadian disruption to obesity and diabetes.

A new study suggests that an extra cup of joe may help people survive longer with prostate cancer if they are fast caffeine metabolizers. 

An innovative device decentralizes blood collection and unlocks a new horizon for blood-based biomarker discovery.

The words “diet” and “exercise” are synonymous with weight loss. Researchers now think that “pharmacotherapy” should be too.

Implanting brown fat into mice fed a high fat diet helps them lose weight and become glucose tolerant. Will it do the same for humans?

By studying the metabolic pathways that go awry in the placenta, scientists found a molecule that restores normal cellular function in preeclampsia.

An obesity medicine clinician researcher propels a growing movement to normalize obesity as a disease that requires long-term treatment.