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Immunology
| 8 min read
With new insight into IgE biology, a new, two-pronged strategy for eliminating the pathogenic immune cells that lead to allergies emerges.
Monoclonal antibodies are life-saving therapeutics that can be used for a myriad of conditions from infectious diseases to cancer.
| 4 min read
A novel immunotherapy targets the liver to promote tolerance to allergens in mice, promising durable allergy relief without the risk of severe reactions.
| 5 min read
IO Biotech’s two-pronged cancer vaccine targets tumors and the suppressive immune cells around them, demonstrating promising results in metastatic melanoma.
| 8 min read
A new approach for gene editing will get its shot in a common and chronic autoimmune disorder.
| 4 min read
During mold infection, a cytokine sends signals to neutrophils to kill invading fungal spores in the lungs, enhancing survival.
| 4 min read
The therapy lengthened telomeres and improved immune function in people with telomere biology disorder, showing promise for treating bone marrow failure safely.
| 4 min read
Uniquity Bio seeks to investigate compounds that might otherwise sit on the shelf forever. Their lead compound appears poised to prove their model works.
| 3 min read
Immune cells carried an antioxidant to a mouse’s cardiac muscle cells, which had been damaged by a heart attack.
| 3 min read
Omalizumab could be a better treatment for children with food allergies compared to oral immunotherapy, mainly due to fewer side effects.
| 4 min read
Researchers developed a PET probe that targets all immune cells to help diagnose and monitor inflammatory diseases.
| 7 min read
A targeted interleukin-12 gene therapy plus chemotherapy increased survival in advanced ovarian cancer, setting the stage for a new first-line drug.
| 6 min read
ArsenalBio equips T cells with multiple weapons to identify, attack, and persist against tumors, bringing the power of CAR T cell technology to solid cancers.
| 2 min read
Antibiotics target bacteria, but new work in mice shows they also harm the mucus layer that protects the intestinal lining from microbes.
| 2 min read
Researchers revealed for the first time that CAR T cells can transfer their CAR molecules to regular T cells in a process known as trogocytosis.
Available on Demand
Learn about the immunomodulatory role and therapeutic potential of extracellular matrix components.
| 4 min read
As a CD40 ligand antagonist, dazodalibep blocks immune cell communication, potentially serving as the first drug to target the autoimmune disease’s cause.
| 4 min read
A strain of E. coli linked to Crohn’s disease produces a compound that triggers intestinal scarring, revealing a potential treatment path.
| 4 min read
N-cadherins in smooth muscle cells play an important role in constricting bronchi, but inhibiting the protein could provide relief to patients with asthma.
| 3 min read
Ovarian tumors are extremely difficult to get rid of. Scientists are figuring out how to leverage the immune system to help.
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