Advances in cell biology and recent policy changes are reshaping preclinical research. The FDA Modernization Act has accelerated interest in human primary cell models as alternatives to traditional animal systems. Immune coculture models offer new ways to capture the complexity of human biology in vitro. In this webinar, Ethan Shelkey will examine epithelial–immune and cancer–immune coculture systems for studying infection, immunity, and therapeutic response with case examples highlighting how these models improve physiological relevance and support safety and efficacy assessment.
Topics to be covered:
- Key implications of the FDA Modernization Act for preclinical testing
- Modeling lung inflammation with bronchial epithelial–peripheral blood mononuclear cell cocultures
- Applications of immune coculture systems in cancer therapy testing and toxicity assessment
Wednesday, October 15th, 2025 | 11:00 AM - 12:00 PM Eastern Time
This webinar will be available to view live and on demand.
Speaker
Ethan Shelkey, PhD
Research Scientist
Lonza
