Ophthalmology

In diabetic macular edema, senescent cells build up in the retina, leading to vision loss. A new drug forces these undead cells to die, healing the retina.

Researchers are developing next-generation contact lenses that combat the disrupted fluid dynamics behind contact lens-induced dry eye syndrome.

Spaceflight Associated Neuro-ocular Syndrome impairs astronauts’ vision, but new strategies to study the condition in space and on Earth may lead to treatments.

James Fujimoto, Eric Swanson, and David Huang developed optical coherence tomography, which transformed ophthalmological practice and spurred new imaging applications.

Cell therapies derived from stem cells could one day prevent vision loss or even restore sight in retinal degenerative disease.

Injecting healthy, exogenous mitochondria into the eye could combat mitochondrial dysfunction and cell death in Fuchs endothelial corneal dystrophy.

To dismantle healthcare barriers in low-resource areas, researchers measure the color signatures of jaundice and anemia using a device that’s in everyone’s pocket.

Eye injections are the only way to treat diabetic retinopathy, but many refuse to get them. Now, eye drops and pills are on their way.

Researchers correcting the genetic causes of disease at the DNA or RNA level make their cases.

Neuroscientists safely delivered a critical gene that improved vision for two patients with Leber congenital amaurosis.

A new analysis shows huge variation in mutations for induced pluripotent stem cells, including some changes that can severely limit their ability to transform into other kinds of cells.

Wolfram Syndrome is a rare disease that causes a myriad of challenges, including deafness, diabetes, and depression. New research suggests that an agonist used to treat neurodegenerative disorders may help alleviate some of the symptoms.

Silicon nanoneedles loaded with ocular drugs hold potential to replace invasive injections to the eye.

Age-related macular degeneration is the most common cause of vision loss in adults over age 50, but there are few treatments available. Researchers are now developing promising stem cell therapies to treat the disease.

Researchers are developing gene and cell therapies and prosthetics to help patients with blindness regain some vision. The first major prosthetic, the Argus II, was just discontinued. Where will the field go from here?

Between invasive surgery or risky laser therapy, people suffering from severe eye floaters have no great treatment options. Now, with the development of a safer and less invasive nanoparticle-based therapy, people with floaters may finally get their vision and quality of life back.

Researchers pioneered a new strategy for diagnosing puzzling genetic diseases, expanding scientists’ capability to study their causes and pathophysiology.

Scientists identify a new target for treating age-related eye diseases

ABIONYX achieves positive clinical results with CER-001 in familial lecithin–cholesterol acyltransferase deficiency

Data show full complement ST266 biologic offers better neuroprotection than fractionated formats