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Ophthalmology
| 7 min read
To get drugs to reach the choroid and retina, ophthalmologists have relied on imperfect methods with drawbacks. Suprachoroidal delivery could be the fix.
| 5 min read
Via a unique regulatory route in the UK, scientists found that a gene therapy restored vision in young kids with a very rare and severe retinal dystrophy.
| 9 min read
Galimedix has recruited people with dry AMD to test the efficacy of their drug, which disrupts the same toxic beta-amyloid oligomers implicated in Alzheimer’s disease.
| 2 min read
Plummeting blood sugar can accelerate eye damage due to diabetes. Results in mice suggest that a new drug targeting hypoxia inducible factor could help.
| 2 min read
Researchers discovered an immunological connection between the eye and the brain that could lead to new therapeutics for central nervous system diseases.
| 10 min read
People with achromatopsia have never seen color. Restorative gene therapies have had mixed success, leaving researchers wondering why.
| 8 min read
Researchers use retinal organoids to screen drugs and hope to transplant them into the eyes of people with blindness in the coming years.
| 8 min read
In diabetic macular edema, senescent cells build up in the retina, leading to vision loss. A new drug forces these undead cells to die, healing the retina.
| 9 min read
Researchers are developing next-generation contact lenses that combat the disrupted fluid dynamics behind contact lens-induced dry eye syndrome.
| 10+ min read
Spaceflight Associated Neuro-ocular Syndrome impairs astronauts’ vision, but new strategies to study the condition in space and on Earth may lead to treatments.
| 3 min read
James Fujimoto, Eric Swanson, and David Huang developed optical coherence tomography, which transformed ophthalmological practice and spurred new imaging applications.
| 9 min read
Cell therapies derived from stem cells could one day prevent vision loss or even restore sight in retinal degenerative disease.
| 9 min read
Injecting healthy, exogenous mitochondria into the eye could combat mitochondrial dysfunction and cell death in Fuchs endothelial corneal dystrophy.
| 10 min read
To dismantle healthcare barriers in low-resource areas, researchers measure the color signatures of jaundice and anemia using a device that’s in everyone’s pocket.
| 10+ min read
Eye injections are the only way to treat diabetic retinopathy, but many refuse to get them. Now, eye drops and pills are on their way.
| 7 min read
Researchers correcting the genetic causes of disease at the DNA or RNA level make their cases.
| 4 min read
Neuroscientists safely delivered a critical gene that improved vision for two patients with Leber congenital amaurosis.
| 5 min read
A new analysis shows huge variation in mutations for induced pluripotent stem cells, including some changes that can severely limit their ability to transform into other kinds of cells.
| 3 min read
Wolfram Syndrome is a rare disease that causes a myriad of challenges, including deafness, diabetes, and depression. New research suggests that an agonist used to treat neurodegenerative disorders may help alleviate some of the symptoms.
| 4 min read
Silicon nanoneedles loaded with ocular drugs hold potential to replace invasive injections to the eye.
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