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Neuroscience
Neuroscience
| 4 min read
by
Andrew Saintsing, PhD
Unlocking brain health with an extracellular vesicle biomarker
The protein APLP1 strongly associates with brain-derived EVs. A blood test could one day isolate these molecular packets to diagnose neurological disorders.
News
| 3 min read
by
Jennifer Tsang, PhD
First brain-delivered AAV therapy approved by FDA
The gene therapy treats the rare genetic disease AADC deficiency by delivering a functional gene into the brain.
News
| 3 min read
by
Gillian Dohrn
Reinforced oxytocin quells chronic abdominal pain in mice
Researchers developed a new pill with promising applications for treating pain due to gastrointestinal disorders.
News
| 5 min read
by
Allison Whitten, PhD
and
Stephanie DeMarco, PhD
Predicting 2025’s biggest innovations in drug discovery
Industry leaders predict the most exciting advances in drug discovery and development in the coming year.
News
| 4 min read
by
Laura Dattaro
Glioblastoma astrocytes are stuck in immaturity
Genetic analysis of organoids and brain tumors showed that the cancers are packed with cells that haven’t reached a mature state.
News
| 3 min read
by
Carolyn Bernhardt
With a protein boost, nucleotide drugs get to the brain
An oligonucleotide transport vehicle could transform neurological disease treatment by enhancing drug delivery across the blood-brain barrier.
News
| 3 min read
by
Nora Bradford
Hope for Niemann-Pick type C in FDA’s dual drug approval
The FDA approved two new medications for Niemann-Pick disease type C that improve symptoms, showing the power of community advocacy.
News
| 3 min read
by
Michael Schubert, PhD
Sponsorship effect: how drug manufacturers bias clinical trials
New research revealed that manufacturer-funded clinical trials deem drugs more effective than non-sponsored trials.
News
Available on Demand
by
Drug Discovery News
Understanding neuroinflammation in Parkinson's disease
Explore the role and cellular mechanisms of neuroinflammation in Parkinson’s disease.
Webinars
| 1 min read
by
Yuning Wang, PhD
Explained: What is mesenchymal stem cell therapy?
Born to differentiate and heal, mesenchymal stem cells carry great potential for treating a wide spectrum of diseases.
Explainers
| 6 min read
by
Allison Whitten, PhD
Targeting a clotting protein to treat neonatal brain bleeds
Researchers discovered that a blood clotting protein, fibrinogen, harms brain development during bleeds in preterm infants.
News
| 8 min read
by
Allison Whitten, PhD
Gene therapy could treat Alzheimer’s disease
New gene therapies in clinical trials seek to treat Alzheimer’s disease and heal the brain with a dose of helpful genetic material.
News
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Scaling neuronal activity profiling with semi-automated electrophysiology
Advanced microelectrode array and liquid handling technologies make neuronal culture screening more consistent and easier to scale.
Application Note
Modeling neurotropic viral infections using human cerebral organoids
Using fetal-stage brain organoids, researchers are uncovering how Zika virus impacts neurodevelopment and contributes to microcephaly.
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Volume 21 • Issue 4 • December 2025
December 2025
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