Cancer

Genetic analysis of organoids and brain tumors showed that the cancers are packed with cells that haven’t reached a mature state.

Initially thought of as a DNA-damaging drug, 5-fluorouracil mainly kills cancer cells by interfering with ribosomal RNA, opening up new avenues for care. 

As spatial biology rises to prominence, explore the science, milestones, and discoveries driving this rapidly evolving field.

Probing the molecular drivers of brain metastasis reveals novel therapeutic targets.

Computational methods add new options for teasing apart cellular heterogeneity.

A new method for tracking CAR T cells in patients with blood cancers relies on a probe that binds directly to the therapeutic cells’ antigen receptor.

Discover the tools and techniques that help scientists decipher every layer of genetic regulation and gene functions. 

Researchers are tapping into the potential of noncoding RNA in the blood to enhance cancer diagnostics. 

As cell therapy evolves rapidly, what advancements are on the horizon? 

Researchers showed that pancreatic cancer stem cells produce a protein usually made by neutrophils to evade the immune system and keep growing.

Profiling over 100,000 genomes, researchers identified rare mutations associated with early menopause and cancer, and that some mutations pass down to children.

Effective target identification is central to drug discovery, but finding the right drug target is not as simple as it may seem in theory.