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News
| 2 min read
by
Bree Foster, PhD
Llama-derived nanobodies restore cognition in schizophrenia mouse models
The therapy crosses the blood-brain barrier after peripheral injection and delivers behavioral improvements that last up to seven days.
News
| 3 min read
by
Bree Foster, PhD
FDA grants Breakthrough Therapy designation to Duchenne muscular dystrophy therapeutic
This recognition signals momentum for next-gen RNA therapeutics designed to enhance delivery and efficacy in treating rare genetic diseases.
News
| 3 min read
by
RJ Mackenzie
Blood biomarkers offer new targets for ME/CFS drugs
Largest molecular analysis to date reveals more than 100 blood biomarkers tied to the disease.
News
| 5 min read
by
Bree Foster, PhD
Why gene and cell therapies are stalling at the FDA
A wave of FDA rejections reveals how CMC issues are becoming a leading barrier to approval in cell and gene therapy development.
News
| 4 min read
by
DDN editorial team
Weekly Rundown: GSK bets $500M on Hengrui pipeline in licensing pact
Big-ticket licensing, FDA shake-ups, and Alzheimer’s data led the news this week.
News
| 3 min read
by
Andrea Corona
New insights reveal proteins are more stable than we thought
Researchers challenge decades-old assumptions about fragile protein cores, opening new paths for faster drug and enzyme design.
News
| 8 min read
by
Allison Whitten, PhD
To speed patient access, Allogene scales up CAR T cell products
By starting with T cells from healthy donors, Allogene is manufacturing off-the-shelf CAR T cell therapies that patients don’t have to wait for.
News
| 3 min read
by
Andrew Saintsing, PhD
Machine learning drives progress in fibrosis treatment
Insilico’s Phase 2a trial of an AI-designed therapy marks a milestone in data-driven drug development.
News
| 4 min read
by
DDN editorial team
Weekly Rundown: FDA probes Sarepta after third death in gene therapy trial
Another death linked to Sarepta’s gene therapy, a promising glioblastoma trial, a rejection for Replimune, and more led the news this week.
News
| 2 min read
by
Andrea Corona
Chemistry-led approach draws $75.5M for Actithera’s radioligand platform
By focusing on chemistry rather than biology alone, Actithera is aiming to elevate radiopharmaceuticals from niche applications to standard-of-care contenders.
News
| 3 min read
by
Jennifer Tsang, PhD
Detecting menstrual blood biomarkers directly on sanitary pads
Point-of-care tests that detect biomarkers from menstrual blood can enable broader access to disease monitoring and diagnosis.
News
| 4 min read
by
RJ Mackenzie
Proteome analysis reveals personalized diabetes signatures
Researchers showed that insulin resistance exists on a spectrum among diabetics and healthy controls.
News
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Breaking barriers in mRNA therapeutics development
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Comparing spheroids, organoids, and organs-on-chips
Learn how various 3D cell culture systems differ in design, function, and application in biomedical research.
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Volume 21 • Issue 3 • September 2025
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