Philip Yeske was an organic chemist for more than 20 years, but when his daughter died from the rare mitochondrial disorder Leigh Syndrome, he turned to connecting researchers, patients, and law makers to speed the discovery of treatments.
People metabolize drugs differently, changing the effectiveness and toxicity of drugs between individuals. Genetic testing to identify mutations in metabolic genes that may affect how someone processes a drug is an important step towards precision medicine that is becoming more common in the clinic.
Pregnant people with mental health disorders such as depression or bipolar disorder often face an impossible decision: risk their health or their future child's health by discontinuing or continuing their medication.
Researchers plan to monitor the immune responses of COVID-19 patients for one year to see how they correlate with illness severity and lasting effects. This data will help develop personalized treatments for patients.