biochemistry

In vivo studies of the antibiotic darobactin D22 against high-priority gram-negative bacteria show promise for further drug development.

The new complex is inexpensive to produce, and its unique architecture makes chemical reactions integral to drug discovery more stable and efficient.

A new wound dressing monitors infections in real time and administers timely treatment using metal ions.

Researchers designed a nanoparticle that inactivated a wide range of COVID-19 strains, potentially offering a broad-spectrum therapeutic approach.

Mireille Kamariza develops new chemistry-driven diagnostics for tuberculosis that can reduce the time to treatment from weeks to minutes.

Polymer scientist Heather Maynard takes advantage of trehalose’s protective properties to design more stable formulations of life-saving drugs.

A team of global scientists found an antibody-based therapeutic that they hope will stop the next rodent-borne hantavirus outbreak in its tracks.

Antibiotic resistance is on the rise and scientists are on the lookout for new therapeutics for treating human pathogens. One promising new venture repurposes antimalarial drugs to treat patients with chronic lung diseases such as cystic fibrosis.

Membraneless droplet like organelles known as condensates are changing the way some scientists approach drug discovery.

Researchers no longer think that proteins blindly swim through the cytoplasm hoping to bump into one another. Instead, they intentionally aggregate with other biomolecules, forming membrane free, transient organelles called condensates.