Tardigrades are microscopic invertebrates capable of surviving extreme environmental stressors that would prove lethal to most other organisms. Central to this resilience is a unique protein known as Damage Suppressor (Dsup), which binds to chromatin and minimizes DNA breaks caused by ionizing radiation.
In this webinar, Tyler Woodward and Valerie Collins will discuss how they use microfluidic modulation spectroscopy (MMS) to reveal the biochemical and structural mechanisms by which Dsup confers DNA protection, laying the groundwork for Dsup-based and Dsup-inspired therapeutics.
Topics to be covered:
- Molecular strategies used by tardigrades to tolerate extreme environmental stress
- Biochemical properties of the Dsup protein and its role in modulating DNA damage
- Mechanisms of the multivalent interface between Dsup and DNA that influence damage susceptibility
- Applications of MMS for characterizing complex protein–DNA structures
Tuesday, May 5th 2026 | 11:00 AM – 12:00 PM Eastern Time
This webinar will be available to view live and on demand.
Speakers
Tyler Woodward
PhD Candidate
University of Iowa
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Valerie Collins, PhD
Applications Manager
RedShiftBio
