genomics

Cancer cells with mutated p53 undergo apoptosis by stalling ribosomes at rare leucine codons, inhibiting protein translation.

Researchers created an improved method for assays that detect viral vectors in a patient’s blood or urine. It’s used to ensure that bystanders will not be exposed.

Inspired by nature, Peel Therapeutics scientists look to evolution to find the next life changing drug.

Nuclear structures that facilitate DNA repair could lead to new cancer therapies.

Diverse genetic and environmental factors such as stress or UV exposure can spark autoimmune diseases. 

Researchers discovered a new gene required for pancreas development, but much to their surprise, they found that it was absent in all animals except primates.

Multiomics data analysis identified structural mutations in tumor genomes with important implications for cancer treatment.

Researchers identified schizophrenia risk genes that mediate placental, rather than brain, function, revealing new insight into the disease’s developmental origins.

Direct cardiac reprogramming relies on the principles of transdifferentiation to convert specialized cells into new cell types that help repair the heart.

Researchers have uncovered a collection of previously unknown genetic changes in Hodgkin lymphoma cells and reconstructed a timeline of when they develop, paving the way for new treatments.