genomics

Direct cardiac reprogramming relies on the principles of transdifferentiation to convert specialized cells into new cell types that help repair the heart.

Researchers have uncovered a collection of previously unknown genetic changes in Hodgkin lymphoma cells and reconstructed a timeline of when they develop, paving the way for new treatments.

With diseases like cancer and kidney disease on the rise in Africa, Segun Fatumo and his team are sequencing the genomes of 100,000 Nigerians to understand why.

While some pediatric brain cancers have known genetic causes, many do not. Three-dimensional profiling revealed new disease mechanisms and drug targets.

Scientists use metagenomics to explore the viral community inhabiting the human body.

In a journey that spanned the genomes of more than 150,000 Icelanders, archival samples, and a fetus in utero, researchers not only identified genetic variants missing from the population, but also proved that these missing mutations cause three rare genetic diseases.

Intronic DNA sequences are promising targets for developing anti-cancer therapeutics.

What do 23andMe and Snapchat have in common? They both collect very personal information about their users. Do the benefits outweigh the risks?

Advances in data integration enable scientists to combine multiomics data and a patient’s clinical record to develop precision medicine approaches for treating disease.

A recent effort to sequence the entire human genome also revealed how it can be modified.