September 2018 Volume 14, Issue 9
Volume 14, Issue 9 | September 2018
September 2018
In this Issue
Research & Development
Sustaining a market edge
MilliporeSigma, InnoCore enter into agreement to provide SynBiosys biodegradable polymer platformDouble the sequencing
Mount Sinai combines DNA and RNA sequencing to pinpoint treatment options for multiple myeloma patientsBiomarker for breast cancer
Researchers identify a histone that could have significance in treating aggressive breast cancerTuning in to stereochemistry
Scripps, Bristol-Myers Squibb scientists reveal a method to control thiophosphate linkages in nucleosidesDecoding how living tissues get their flexibility
MIT study reveals atomic structure of tropoelastin, showing what goes wrong in some diseasesClinical Trials
Conquering Crohn’s disease
Promising Phase 3 test results give hope for those with the gastrointestinal disorderInitial exuberance overshadowed by doubt
Promising results from Alzheimer’s drug wither under closer scrutinyMogamulizumab makes a mark
Kyowa Kirin announces results of Phase 3 clinical study published in Lancet OncologyOut of the starting gate
A roundup of clinical trial startups and initial breakthroughsZogenix announces positive results for ZX008 in Dravet syndrome
Statistically significant convulsive seizure reduction seen, and all key secondary endpoints metDiscovery
New data about the presence of prions
The identification of prion-like domains in multiple viral strains points to new areas to exploreBack to the beginning
Cells reverting to ‘fetal program’ may accelerate wound healingCMPK2 inhibitors vs. chronic inflammation
Blocking CMPK2 enzyme could mean relief for a host of conditionsBlocking alcohol addiction and easing withdrawal
Scripps Research scientists find novel pathway in the receptor GPR139Immatics and Genmab partner on next-gen cancer immunotherapies
Companies combine proprietary tech to create bispecific therapies against novel tumor targetsSpecial Reports
Special Report on Stem Cells: The next generations
Are stem cells key to fighting infertility?Feature
ASHG 2018 show preview: Covering the breadth of human genetics in San Diego
American Society of Human Genomics Annual Meeting 2018 to showcase the latest on the human genomeEditor's Focus
Editor’s focus: A ‘personalized’ problem in the public space
Way too many people in the United States still don’t know what personalized medicine is, and that’s a problem we need to overcome before the misinformation creeps in too muchCommentary
Out of order: Just being social
We’ve put a greater emphasis on our social media presence lately, and you might want to do the same if you haven’t already, not to mention visit us online
Guest commentary: DNA sequencing is cancer’s next frontier
In the quest for personalized medicine to become reality, next-generation sequencing is keyDiagnostics
Accurate annotations
Bicoastal startup launches NGS product for pathogen detectionThe earlier, the better
Precision’s Epiontis ID diagnostic detects many rare, severe immune diseases in newbornsHeadsUp for cystic fibrosis
Study to assess biomarkers associated with onset of pulmonary problems and validate diagnostic for self-monitoringPredicting checkpoint blocker response
Study finds melanoma biomarkers that could help in tailoring immunotherapyBusiness & Government Policy
It’s all in the delivery
Checking out the news in drug delivery advancementsX-SCID expertise
Mustang Bio and St. Jude enter license agreementReducing cancer trial barriers
Two research organizations submit recommendations to FDA aimed at greater patient participation in trialsOn the cutting edge
A roundup of instrumentation, software and other tools and technology newsPatent Docs: Allergan, a Mohawk tribe and the USPTO
Federal Circuit decision addresses dispute between Allergan and the St. Regis Mohawk Tribe, tackling the issue of sovereign immunityContract Services
Catalent snaps up Juniper Pharmaceuticals
$133-million deal adds European Early Development Center of Excellence to global networkRiding the Seventh Wave to future growth
BASi acquires Missouri-based contract lab Seventh Wave, expanding service offerings, doubling clientsLifeSci launches LifeSci Strategic Partnering and Analytics
New offering will give clients expertise and assistance in business development and market analyticsPreclinical
Good news for Siamab with Stn
New antigen target shows promise against ovarian cancerArticle elucidates ITI-214’s mechanism of action
Modulation of adenosine A2B receptor signaling pathway increases cardiac contractility without increasing intracellular calciumMaking the (pre)clinical rounds
A collection of news of recently published papersCertis partners with Reveal Biosciences
Duo will offer advanced preclinical oncology servicesQ&A
Q&A: SK Life Science and the central nervous system
We speak with Dr. Marc Kamin, chief medical officer of SK Life Science, about the company and CNS disorder therapeutics
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Discovering deeper insights into malaria research
Malaria continues to drive urgent research worldwide, with new therapies and tools emerging to combat the parasite’s complex lifecycle and global burden.
Accelerating RNA therapeutic testing with liver microphysiological platforms
Researchers can now study oligonucleotide delivery and efficacy in a system that models a real human liver.
Shining light on the subcellular proteome
Discover how innovative proteomics tools help researchers peer into once inaccessible organelles, allowing for new targets for drug discovery and development.
