SBS New Product Showcase

Synergy 2 Multi-Detection Microplate Reader uses a monochromator, filters and dichroic mirrors providing high performance in detection modes including Fluorescence Intensity, Fluorescence Polarization, Time-Resolved Fluorescence, Luminescence and UV-Vis Absorbance. Three broad-spectrum light sources provide optimal illumination and excitation. Synergy 2 is modular for customization, equipped with temperature control, shaking, monochromator-based photometry and a reagent injection system, and controlled by Gen5 Data Analysis software.

Glass-Bottom Microplates Coated for Cell Culture Applications—Cell culture coatings including poly-D-lysine, collagen and more are now offered for all glass-bottom microplates. Coated glass-bottom plates in 24-well, 96-well, 384-well and even 1536-well are available. A wide variety of other TC and assay surface coatings on glass-bottom plates are also available on request.

The Patchliner is Nanion's fully automated patch clamp workstation with increased throughput and full experimental freedom. The instrument is applicable in safety pharmacology, target validation and in ion channel research. The system has eight amplifier channels to perform simultaneous recordings and utilizes Nanion's NPC-16 chips, which allows for a rapid and precise compound application to the cell's external and internal side.

The Finnpipette Novus is the first electronic pipette to have a backlit display. By eliminating light reflections and improving contrast, menu characters are shown with greater clarity. In addition, Thermo Scientific's market-leading two-year warranty for all its electronic pipettes means that the Finnpipette Novus range is now even more user-friendly, improving productivity, precision, ergonomic operation and peace-of-mind.

Use Invitrogen's powerful LanthaScreen TR-FRET Technology to interrogate inhibitors of the FRAP1 kinase PV4753 (10 µg). Our LanthaScreen Toolbox now includes a known substrate for FRAP1 kinase expressed as GFP fusion protein (GFP-4E-BP1 20 nmol PV4759) and an antibody specially designed to detect phosphorylation of this substrate (Tb-anti-4E-BP1 (pThr46) 25 µg- PV4757 and 1 mg -PV4758).

Genetix CellReporter is an ultra-sensitive, non-invasive, live-cell assay system which rapidly images and analyses multiple-wavelength fluorescent read-outs from a wide range of key cell-based assays. CellReporter enables straight forward data mining through intuitive software, facilitating confident decision making in cellular analysis and lead optimization in drug discovery. CellReporter's synchronized imaging enables super fast analysis and delivers quantitative measurements of apoptosis, cytotoxicity, cell viability and proliferation with minimal reagent requirements.

The MDL Assay Explorer system provides an integrated environment for the capture, visualization, analysis and storage of all types of biological results. With the new Assay Explorer for Excel user interface in Assay Explorer 3.1, scientists can create and view experiments directly in Microsoft Excel spreadsheets while maintaining consistency of terminology and calculations through Assay Explorer.

The BD Gentest Pre-Coated PAMPA Plate System is a 96-well insert system with a PVDF filter plate which has been pre-coated with structured layers of phospholipids and a matched receiver microplate. The BD Gentest Pre-Coated PAMPA Plate System has been validated for use in PAMPA and comes ready to use in your assay.

Enbiotec Laboratories Co. Ltd., an environmental biotechnology company, has developed the Receptor Cofactor Assay System (RCAS) as a screening tool to detect the ligand-dependent binding between nuclear hormone receptors and cofactors in vitro. The screening system is cell-free, highly sensitive, and is able to distinguish between agonist and antagonist compounds.

The Thermo Scientific Varioskan Flash is a spectral scanning multimode microplate reader featuring unlimited wavelength selection with spectral scanning for TRF, fluorometric, luminometric and photometric assays. Our product offers easy integration and the capability to read up to 1536-well plates.

For more information contact Thermo Fisher Scientific, www.thermo.com/mpi

Hit Profiler is an easy-to-use, scientifically validated solution for efficient hit and lead assessment. The compound-centric, interactive table environment identifies promising leads based on biological, chemical, pharmacological and other parameters. Hit Profiler has been developed alongside industry experts and provides a corporate platform supporting the lead selection teams in communicating effectively.

 

The inherent complexity of GPCR signaling demands simple, robust technologies for quantifying receptor activation. The new cAMP-Glo Assay provides the simplest method available for measuring Gs- or Gi-coupled receptor activity. Wide dynamic range and high sensitivity make the assay ideally suited for 1536-well plate applications.

 

The new miVac pressure controller gives accurate pressure readout at all stages of sample concentration and provides full control of pressure and vacuum ramping capability. Unlike 'open-access' blowdown evaporator systems miVac sample concentrators with pressure control minimise the dangers of sample cross-contamination and enhance solvent recovery. The miVac sample concentrator range was designed to meet the requirements for careful and speedy drying in most biological applications. Special methods for drying aqueous and alcohol-based samples are included in all the miVac models.