PROTAC: hitting the mark on cancer

By directly and precisely destroying troublesome proteins, PROTAC molecules emerge as effective tools for enhancing cancer treatment.

Human cells have a built-in protein waste disposal mechanism known as the ubiquitin-proteasome system that eliminates undesirable proteins. Researchers harness this natural mechanism to create proteolysis-targeted chimera (PROTAC) molecules that precisely degrade cancer-causing proteins, offering a promising approach for developing targeted cancer therapies.

Download this poster from Drug Discovery News to explore the principles of PROTAC therapy and its multifaceted mechanisms for effectively combating cancer.