Cancer progresses more rapidly with age. Aging brings about alternated cellular functions, disrupted cell-cell interactions, and weakened immune responses within the tumor microenvironment (TME). A deeper understanding of these changes observed in mice may unlock new ways to target aging’s effects in cancer therapies.
In this 20-minute video, you’ll learn
- How does the aged TME promote T cell and dendritic cell dysfunction?
- How can mouse models help uncover immune dysfunction mechanisms in the aged TME?
- What are the cytokine changes in the aged TME?
- Can the aged TME be reinvigorated?