When the immune system mistakenly identifies the body’s tissues or cells as foreign, it produces autoantibodies that can lead to various autoimmune diseases and neurological disorders. However, identifying specific autoantibodies among the vast diversity of antibodies is challenging. In this webinar brought to you by Bruker Cellular Analysis, Michael Wilson and Vincent Pai will discuss how they used advanced single B cell screening to discover autoantibodies that hinder vitamin B12 transport across the blood-brain barrier in a patient with severe neurological deficits, revealing a novel autoimmune condition and potential treatment options.
Topics to be covered
- Isolating disease-specific, patient-derived monoclonal antibodies for pathophysiology research
- Rapid functional screening of single B cells for therapeutic antibody and biomarker discovery
Monday, October 28th, 2024 | 1:00 PM - 2:30 PM Eastern Time
This webinar will be available to view live and on demand.
Speakers
Michael Wilson, MD
Professor
University of California, San Francisco
Vincent Pai
Director of Product Management
Bruker Cellular Analysis