Immunotherapy empowers immune cells to target cancer, achieving dramatic results in some cases. Yet many tumors evade detection or suppress immune activity, with outcomes shaped by tumor-intrinsic mechanisms, the microenvironment, and broader host factors.
In this Explainer Article, explore:
- Why some tumors evade immune recognition and resist treatment
- How the tumor microenvironment and patient biology shape outcomes
- New approaches to overcome barriers and extend benefits across cancer types
