Metabolites and drug metabolites offer a window into biology in action. Their changing profiles can reveal how disease progresses, how the body responds to treatment, and how drugs are transformed, providing valuable clues about efficacy, safety, and biological function.
From metabolite biomarkers to structural characterization of drug metabolites, this compendium covers the role of metabolites in drug discovery and the analytical approaches used to identify them, including liquid chromatography–tandem mass spectrometry (LC-MS/MS), targeted and untargeted analysis, and fragmentation strategies.
Download this compendium to learn:
- How metabolite biomarkers can reveal disease mechanisms
- How LC-MS/MS workflows support metabolite detection, structural characterization, and identification
- How advanced fragmentation approaches can improve confidence in identifying challenging drug metabolites
