The promise of CAR macrophages

T cells have long held the title of the ideal immune cells for CAR therapy, but recent discoveries are opening new possibilities for other immune cells.

Macrophages are potent killer cells adept at consuming and eliminating abnormal cells in the body. This, coupled with their unique ability to penetrate the solid tumor microenvironment and mediate immunosuppression, makes them attractive for a new type of chimeric antigen receptor (CAR) therapy. In this webinar, Denise Montell will discuss how studies on cell movement and phagocytosis in fruit flies revealed a universally conserved protein with the potential to enhance CAR macrophage activity and targeting. 

Topics to be covered

  • Studying cell movement to uncover the mechanism behind a rare human immunodeficiency
  • Harnessing this molecular mechanism to enhance CAR macrophage immunotherapy

Thursday, May 23rd, 2024 | 1:00 PM - 2:00 PM Eastern Time
This webinar will be available to view live and on demand.


Denise Montell, PhD

Denise Montell, PhD

Distinguished Professor
University of California, Santa Barbara

Supported by