Biotherapeutic proteins often exist in multiple forms with slight differences in electric charge, known as charge variants, which can affect stability, efficacy, and safety. Analyzing these variants is a key part of biologics development, and the gold standard method is imaged capillary isoelectric focusing (icIEF). As sample numbers increase, scientists are seeking strategies to improve productivity and throughput. In this webinar, Michael Grasso and Will McElroy will present an advanced approach to icIEF that significantly reduces analysis time while preserving data quality, offering a practical solution for accelerating biotherapeutic characterization.
Topics to be covered:
- An icIEF method that achieves a 2.5-fold reduction in analysis time without reducing resolution
- How this accelerated icIEF method can be seamlessly integrated into existing workflows
- The feasibility of the faster icIEF approach across a range of biologic molecule types
Tuesday, September 16th, 2025 | 11:00 AM - 12:30 PM Eastern Time
This webinar will be available to view live and on demand.
Speakers
Michael Grasso, PhD
Sr. Scientist
Merck & Co.
Will McElroy
Staff Scientist
Bio-Techne
