3D illustration of DNA and RNA strands with elements representing gene editing and genetic modification.
Webinars

Selecting disease-relevant models to derisk drug discovery

Explore how advanced in vitro and in vivo model systems combined with high-throughput CRISPR screening improve translational confidence.

Brought to you byLonza

The success of target validation and lead optimization depends heavily on how closely a biological model mimics the complexities of human disease. Discrepancies between experimental environments and clinical pathology often lead to late-stage attrition in drug development. 

In this webinar, Melanie Homberg and Kevin Grady will discuss strategies for integrating high-throughput CRISPR screens and advanced biological models to accelerate drug discovery workflows.

Topics to be covered:

  • Criteria for selecting disease-relevant models to improve target validation
  • High-throughput CRISPR screening methods for identifying novel targets
  • Advanced in vitro and in vivo models for enhancing translational success
  • Practical approaches to align model selection with tissue and safety requirements



Wednesday, April 22nd 2026 | 11:00 AM – 12:00 PM Eastern Time
This webinar will be available to view live and on demand.


Speakers

Melanie Homberg, PhD

Melanie Homberg, PhD
Market Development Manager
Lonza

Kevin Grady

Kevin Grady
Associate Director, Market Strategy
Lonza

Sponsored by

  • lonza logo

Top Image Credit:

iStock: luismmolina