CRISPR/Cas9 enables precise genetic modifications that may solve an array of diseases, but off-target CRISPR/Cas9 activity could lead to unintended mutations and risks such as organ damage or immunogenicity. Scientists are developing various safety switches, such as anti-CRISPRs and high-fidelity Cas9s, to enhance the precision and reliability of this transformative technology.
Download this poster from Drug Discovery News to learn about innovative strategies to improve CRISPR/Cas9’s safety profile and reduce the risk of off-target effects.