Serial dilution is a fundamental technique in drug discovery, microbiology, and molecular biology for quantifying analytes, determining minimum inhibitory concentrations, and preparing samples for downstream analysis. Although conceptually straightforward, errors introduced during repeated dilution and mixing steps can accumulate, affecting accuracy, precision, and reproducibility. Careful liquid handling practices and optimized mixing strategies are therefore essential for generating reliable experimental results.
This application note examines automated approaches to serial dilution, including optimized liquid handling parameters, mixing strategies, and workflows that improve consistency while minimizing error propagation.
Download this application note to learn:
- Best practices for accurate two-, five-, and 10-fold serial dilutions
- Mixing strategies that improve dilution accuracy and reproducibility
- Workflow considerations for reducing manual variability and error propagation
