Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease marked by the progressive loss of motor neurons and microglia. Despite decades of research, many aspects of its underlying biology remain unclear. Advances in stem cell technology now make it possible to generate motor neurons and microglia from pluripotent stem cells, offering researchers powerful tools to study disease mechanisms in a controlled, human-relevant system.
Download this whitepaper to learn:
- How stem cell-derived models help capture disease-relevant features of ALS
- Insights into cellular dysfunctions that contribute to motor neuron degeneration
- How these models support drug research and the search for new treatment strategies
