Amyotrophic lateral sclerosis (ALS) involves complex, multicellular dysfunction extending beyond motor neuron degeneration. Emerging research highlights the role of immune cells, particularly microglia, in shaping disease progression. Human stem cell–derived models offer a physiologically relevant system to investigate these interactions and uncover measurable disease phenotypes.
Download this whitepaper to learn:
- How stem cell-derived models help capture disease-relevant features of ALS
- Insights into cellular dysfunctions that contribute to motor neuron degeneration
- How these models support drug research and the search for new treatment strategies
