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Infographics

Checking AAV capsid quality before downstream processing

Learn how upstream analytical strategies can improve AAV yield, quality, and process efficiency.

Adeno-associated virus (AAV) production is a complex, multistep process. Inconsistent batch quality, the presence of empty or partially filled capsids, and process-related impurities can all undermine therapeutic performance — yet most analytical methods are applied late in the workflow, limiting the opportunity to detect and correct problems before significant time and resources have been spent.

This infographic explores how mass photometry enables rapid, high-resolution analysis of capsid populations directly from upstream samples, showing where the technique fits within the AAV production workflow and how it can support more efficient, informed process development.

Download this infographic to learn:

  • How upstream analysis can reveal critical quality attributes, such as empty, full, and partially filled capsids, before downstream processing 
  • How mass photometry compares to established capsid characterization methods across key parameters such as upstream applicability, partial capsid resolution, and throughput
  • How to integrate mass photometry into existing AAV process development workflows

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