Metabolite identification can become increasingly challenging when metabolites occur at low abundance, undergo complex biotransformations, or produce fragmentation patterns that provide limited structural information. At the same time, growing compound libraries and evolving drug modalities are increasing the need for workflows that can generate detailed metabolism data efficiently.
This compendium offers a collection of resources on advanced approaches to metabolite identification, covering strategies for increasing throughput, characterizing challenging metabolites, and gaining greater structural insight.
Download this compendium to learn:
- How complementary fragmentation strategies can provide additional structural information for challenging metabolites
- How site-specific fragment information can help distinguish possible biotransformations and localize sites of metabolism
- How higher-throughput and streamlined analytical workflows can support metabolism studies earlier in drug discovery
