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Overcoming a key bottleneck in antibody development
Researchers embrace automation to speed up antibody purification for accelerated therapeutic breakthroughs.
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Mini Organs: Big Discoveries
Novel organ-on-a-chip platforms drive disease research and precision medicine development.
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The Complicated Role of Microbes in Breast Cancer Prognosis
Antibiotic exposure may impact tumor immunogenicity and breast cancer survival.
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The Impact of the Gut Microbiome on Cancer Immunotherapy Efficacy
The complex interplay between bacteria and the tumor microenvironment informs cancer immunotherapy strategies.
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Overcoming the Challenges of Gene Therapy
Scientists tackle AAV gene therapy hurdles, from enhancing efficiency to managing immunogenicity to improve AAV gene therapy efficacy and safety.
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Mapping the Spread of Infections in the Body
Spatial biology studies allow scientists to gain deeper insights into infectious disease transmission and pathobiology across various tissues.
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Developing a Vaccine for Tuberculosis
Immune evasion by infectious pathogens complicates the development of new vaccines.
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Advancing Oligonucleotide Drug Development
Perfecting the molecular building blocks of oligonucleotides is paramount to developing effective nucleic acid-based therapeutics.
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RNA Editing in Brain Health and Disease
Scientists unravel the complexity of RNA editing to gain insights into neurodevelopmental processes and disorders.
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The Promise of Agonist Peptides
Agonist peptides coupled with non-invasive imaging could be the key to overcoming cancer resistance to immunotherapy.
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High Throughput Antibody Characterization
Epitopes reveal unique insights into antibody activity and potency.
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Lessons from Zoonotic Viruses
What do zoonotic spillover events reveal about virus-host biology and how do scientists use these lessons to inform future mitigation strategies?
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Mapping cancer signaling at single cell resolution
Measuring mRNA and protein together at single cell resolution can uncover tumor-specific signaling activity and immune features.
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Mapping immune disease variants at genome scale
Discover how CRISPR and single-cell RNA sequencing can connect disease-associated variants to regulatory elements, genes, and pathways.
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From absorption to metabolism: predicting human oral drug exposure
Explore how human gut-liver models can improve the translation of preclinical findings into clinical pharmacokinetic predictions.
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