Explainers

A close-up view of glowing double helix DNA strands against a dark background, representing synthetic gene assembly
An illustration of a person swallowing a pill as it descends through the esophagus, while a zoom-in view of the pill reveals a mixture of active ingredients and excipients
A digital rendering of floating light blue mRNA stands on a dark background
An illustration of microbes in the intestines on an orange background with callouts to different microbes suggesting their benefits for drug discovery.
A zoomed-in blood vessel from an arm shows a CAR T cell binding to a surface antigen on a cancer cell.
Immune checkpoint inhibitors regulate the immune system. Antibodies block PD-L1 in red on the surface of a cancer cell and immune checkpoints in blue and violet on a T cell.
An illustration of AAV viral particles floating in bioreactors
On the left, a silhouette of a human body jogs while an electrical heart activity signal extends from its heart. On the right, an anatomical structure of the interior of the heart shows the right atrium, right ventricle, left atrium, left ventricle, sinoatrial node, atrioventricular node, pulmonary artery, aorta, bundle of His, and left and right bundle branches. Arrows show the path of blood flow between the heart chambers.
tbd
A 3D rendering of orange cancer cells, based on an electron micrograph, depicts spreading cancer filopodia and metastasis.
A three-dimensional illustration of assorted blue proteins
Discover how immune response is dysregulated in autoimmune diseases.
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Spatial Proteomics
Find out how advanced tissue imaging approaches are enabling researchers to connect complex biological data with clinically meaningful outcomes.
A network of interconnected human icons overlaid on a world map, representing global collaboration and population-scale data connections.
New collaborative initiatives are bringing pharmaceutical R&D together around large-scale datasets to accelerate therapeutic discovery.
Modeling neurotropic viral infections using human cerebral organoids
Using fetal-stage brain organoids, researchers are uncovering how Zika virus impacts neurodevelopment and contributes to microcephaly. 
Drug Discovery News December 2025 Issue
Latest IssueVolume 21 • Issue 4 • December 2025

December 2025

December 2025 Issue

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