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Tripos’ transition: Informatics company lays off 76, eyes business options

Big changes are in the air at Tripos Inc., from streamlining of operations to potential major restructuring down the road—it’s just that no one, not even the leaders of the company, have any firm idea where that change may ultimately lead.
Written byJeffrey Bouley
| 3 min read

ST. LOUIS—Big changes are in the air at Tripos Inc., from streamlining of operations to potential major restructuring down the road—it's just that no one, not even the leaders of the company, have any firm idea where that change may ultimately lead.

The first ripples of change occurred back in mid-December when the company announced it would streamline its Discovery Research business, a process it completed in late January. This came as a result of the conclusion of a $90 million, four-year project designing and synthesizing chemical compounds for Pfizer Inc. Tripos still provides software development and products to Pfizer, but the end of the chemical services contract left Tripos with a financial gap, and so it decided to conduct layoffs at a state-of-the-art facility built in England to carry out the Pfizer deal.

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