The role of CD40L in ALS

ALS TDI was founded in 1999 as a nonprofit biotech by theJohn Haywood family, whose son Stephen had been diagnosed with ALS (he lost hisbattle with the disease in 2006). Over time, the research group moved from theHaywood's basement to the garage, then occupied a couple of small labs, Perrinrecounts. Today, ALS TDI occupies a 15,000 square-foot facility and has plans to move up to 26,000 square feet inthe near future. Focused on meeting this urgent unmet medical need, ALS TDIexecutes a robust target discovery program, while simultaneously operating theworld's largest efforts to preclinically validate potential therapeutics,including a pipeline of dozens of small molecules, protein biologics, genetherapies and cell-based constructs. Believed to be the world's first nonprofitbiotech, ALS TDI has developed an industrial-scale platform that allows for thedevelopment and testing of dozens of potential therapeutics each year. Withmore than 30 professional scientists, the research Institute collaborates withleaders in both academia and industry to accelerate ALS therapeutic development.