<strong><br></strong><div class="old-content"><strong> </strong><style></style><div class="old-content"><strong></strong><div class="old-content"><strong>The Pistoia Alliance</strong><div class="old-content"><div class="old-content"> </div><div class="old-content"><div class="old-content">HELM software toolkit and editor now available under opensource license.<div class="old-content">HELM (Hierarchical Editing Language for Macromolecules)enables the representation of biomolecules whose size and complexity renderexisting small-molecule and sequence-based informatics methodologiesimpractical or unusable.<div class="old-content"> <div class="old-content"><div class="old-content"> </div><div class="old-content">Offering includes:<li"><br></li"><ul><li><li">Software toolkit     containing functionality needed to implement a HELM-based system</li"></li><li><li"><li">Fully functioning editor     for drawing macromolecules and generating HELM notation</li"></li"><div class="old-content"> <div class="old-content"></div></div></li></ul><div class="old-content"><div class="old-content"><div class="old-content"> </div><div class="old-content"><strong>The Pistoia Alliance </strong><br></div><div class="old-content"><div class="old-content"><a href="http://www.pistoiaalliance.org/ " target="_blank">www.pistoiaalliance.org</a><div class="old-content">  </div></div></div></div></div></div></div></div></div></div></div></div></div> </div></div>

July 2013

HELM software toolkit and editor now available under open source license.

Internal Medicine

The Pistoia Alliance releases 

HELM biomolecular representation standard open-source tools

Article

Articles

ddn-front-cover-december-issue-2025

December 2025

Research Areas

A 3D molecular visualization of antibody-like protein structures with attached yellow payloads floating against a dark, space-like background.

istock-1715913285-1800x900-1

xdc-logo-01-1

Evolving approaches to conjugation chemistry and linker&ndash;payload design are helping address persistent challenges in bioconjugate development.

Advancing bioconjugate development through innovative approaches

Whitepaper

Fluorescent-style illustration of spherical embryonic stem cells clustered together against a dark background.

87742-january-13th-webinar-lonza-kr1800x900-plain-istock

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Lonza

Explore how emerging <em>in vitro</em> systems &mdash; built from primary cells, cocultures, and vascularized tissues &mdash; are improving translational research outcomes.&nbsp;

Advancing predictive <em id="isPasted">in vitro</em> models

Webinars

3D illustration of ciliated cells, with cilia shown in blue.

istock-956478190-1800x900

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Syncell

Ultraprecise proteomic analysis reveals new insights into the molecular machinery of cilia.

Mapping the hidden proteome of elusive organelles

Application Note

The Pistoia Alliance HELM software toolkit and editor now available under opensource license. HELM (Hierarchical Editing Language for Macromolecules)enables the representation of biomolecules whose size and complexity renderexisting small-molecule and sequence-based informatics methodologiesimpractical or unusable. Offering includes: Software toolkit     containing functionality needed to implement a HELM-based system Fully functioning editor     for drawing macromolecules and generating HELM notation The Pistoia Alliance www.pistoiaalliance.org

The Pistoia Alliance releases HELM biomolecular representation standard open-source tools

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July 2013

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