tumor microenvironment

The therapy exploits the properties of a neutrophil-derived enzyme to selectively kill tumor cells while preserving healthy immune cells.

Advances in biofabrication and regulatory momentum are accelerating the move from 2D cultures and animal models to scalable, human-relevant systems.

Discover how coculture models and CRISPR tools reveal new insights into tumour microenvironments.

Metabolic conditioning is emerging as a powerful strategy to enhance the potency, persistence, and manufacturability of next-generation cell therapies, providing new hope for hard to treat cancers.

Autophagy in cancer is a double-edged sword: It protects cells from malignant transformation, but once tumors form, it helps them thrive.

A targeted interleukin-12 gene therapy plus chemotherapy increased survival in advanced ovarian cancer, setting the stage for a new first-line drug.

Ovarian tumors are extremely difficult to get rid of. Scientists are figuring out how to leverage the immune system to help.

Probing the molecular drivers of brain metastasis reveals novel therapeutic targets.

How are scientists incorporating oncolytic viruses into the current cancer treatment landscape? 

Cancer anywhere in the body can change brain activity, and brain activity can drive cancer growth. These surprising discoveries are leading to new treatments.