structural biology
| 4 min read
GPCRs drive a huge portion of today’s drug market, but producing them in a functional form remains a major bottleneck for discovery and structural studies.
Discover how small molecule assemblies interact with protein aggregates to promote their breakdown in neurodegenerative diseases.
| 3 min read
How a team at Pfizer turned a decade-old compound into the fastest small molecule drug for COVID-19.
| 4 min read
Researchers are turning bacterial transport systems from obstacles into opportunities for targeted therapy.
| 4 min read
Scientists are using insights from viral hijacking to chemically reprogram E3 ligases, opening new opportunities in drug discovery.
| 3 min read
Structural insights reveal how DCAF2 can be harnessed to target previously untouchable proteins for degradation.
| 4 min read
The general anesthesia drug propofol restores function to mutated signaling channels associated with epilepsy.
| 4 min read
Researchers uncovered the structure of the measles fusion glycoprotein and identified a neutralizing antibody capable of decreasing its virulence.
| 10+ min read
Learn how structure-based drug design uses a protein's 3D structure to create precisely targeted medicines. Explore the key techniques, from X-ray crystallography to AI-powered modeling.
| 3 min read
Fully synthetic approaches expand the repertoire of possible antimicrobials to overcome existing antibiotic resistance mechanisms.
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