small molecule drugs
| 4 min read
Eli Lilly’s oral orforglipron and Novo Nordisk’s higher-dose WeGovy could be approved on an extremely accelerated timeline.
| 5 min read
Early clinical data suggest that intratumoral delivery may halt tumor activity and support bone regeneration in metastatic breast cancer.
| 7 min read
While amyloid plaques form first, new work suggests targeting tau tangles that spread through the brain could also help the fight against this devastating disease.
| 4 min read
Radiprodil is in development as the first therapy designed to directly address the underlying biology of GRIN-related neurodevelopmental disorder.
| 3 min read
How a team at Pfizer turned a decade-old compound into the fastest small molecule drug for COVID-19.
| 3 min read
People with erythropoietic protoporphyria (EPP) must go to great lengths to avoid sun exposure. There have been no approved treatments that address the disease mechanism, but a new drug could change that.
| 2 min read
A new class of small-molecule drugs could represent a therapeutic modality aimed at eliminating disease-causing proteins before they spread in the body.
| 2 min read
A disease once synonymous with a shortened lifespan is now a model for how drug discovery can directly alter the natural history of genetic disorders.
| 4 min read
Discover how ubrogepant provides migraine relief during the prodrome phase, easing symptoms before headaches fully develop.
| 5 min read
A groundbreaking approach targets muscle stem cells to restore regeneration in Duchenne muscular dystrophy, offering new hope beyond traditional dystrophin-focused therapies.
