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PROTAC
PROTAC
| 4 min read
by
Bree Foster, PhD
Viral biology inspires new approach to rewire enzymes for targeted protein degradation
Scientists are using insights from viral hijacking to chemically reprogram E3 ligases, opening new opportunities in drug discovery.
News
| 3 min read
by
Bree Foster, PhD
A new enzyme is expanding the arsenal for targeted protein degradation
Structural insights reveal how DCAF2 can be harnessed to target previously untouchable proteins for degradation.
News
| 4 min read
by
Kristin Riching, PhD
Capturing degrader efficacy through live-cell kinetics
Live-cell kinetic assays provide time-resolved insights into degrader pharmacology, supporting both lead prioritization and translational modeling.
Articles
| 6 min read
by
Stephanie DeMarco, PhD
New cancer fitness drugs aim to trigger tumor death
Larkspur Biosciences scientists develop drugs that make colorectal cancer tumors vulnerable to killing by the immune system and cell death pathways.
News
| 4 min read
by
Allison Whitten, PhD
Novel endocrine therapies for breast cancer are on the way
Pfizer researchers are developing new treatments to target breast cancer tumors that flourish in the presence of hormones.
News
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