pharmacology

Clinical trial insights refine early-stage toxicology evaluations, yielding safer medicines.

There are currently no FDA-approved drugs to treat vitiligo, an autoimmune disease that kills skin pigment cells. But a phase III study of a drug used to treat atopic dermatitis may be the first to get the FDA seal of approval.

COVID-19 researchers focus their studies on antibodies targeting exposed parts of SARS-CoV-2, but in a new study, a group of researchers showed that antibodies targeting proteins inside the virus are just as important for a robust immune response.

Some scientists use cancer patients as libraries for discovering novel immunotherapies.

An obesity medicine clinician researcher propels a growing movement to normalize obesity as a disease that requires long-term treatment.

Improved chemistry may make RNA editing therapies more feasible in humans.

Age-related macular degeneration is the most common cause of vision loss in adults over age 50, but there are few treatments available. Researchers are now developing promising stem cell therapies to treat the disease.

Membraneless droplet like organelles known as condensates are changing the way some scientists approach drug discovery.

The company plans to develop more specialized, antibody-based GPCR drugs to treat a myriad of diseases. They recruited a leader in overseeing successful clinical trials to get the job done.

By redirecting cells’ endogenous RNA editing machinery, scientists can correct disease-causing mutations, bringing a new kind of gene therapy to the clinic.