A new cell type to fight obesity
Specialized cells in omental adipose tissue may repress fat cell development.
obesity
Targeting nutrient signaling in the gut to tackle metabolic disease
A new oral bead technology is designed to stimulate nutrient-sensing cells in discrete parts of the gut to restore metabolic balance.
The ticking clock of metabolic disease
Mitchell Lazar studies the transcription factors linking circadian disruption to obesity and diabetes.
Food for thought
The words “diet” and “exercise” are synonymous with weight loss. Researchers now think that “pharmacotherapy” should be too.
CRISPR-edited white adipocytes effectively treat diabetes in mice
Implanting brown fat into mice fed a high fat diet helps them lose weight and become glucose tolerant. Will it do the same for humans?
Trailblazing scientist changes the view of obesity
An obesity medicine clinician researcher propels a growing movement to normalize obesity as a disease that requires long-term treatment.
A microbial signal from the gut promotes obesity
Gut microbes produce a metabolite that inhibits the conversion of fatty acids into energy and leads to weight gain in mice.
A new weight loss strategy turns fat into energy
By using extracellular vesicles to target specific neurons in the hypothalamus, scientists induced weight loss in a mouse model of obesity without altering its diet or exercise.
