Mitochondria aren’t just the bean-shaped powerhouses of the cell. They are dynamic organelles that modify their structures to match their functions. Now, new research shows that mitochondrial morphology correlates not only with function, but also with symptom severity in autism.
Mitochondria are dynamic organelles that change their morphology in response to the energetic needs of the cell. But in some disorders such as autism spectrum disorder, mitochondria don't appropriately respond, and the resulting metabolic dysfunction contributes to symptom severity.
When a research question can’t be answered using the tools available, bioengineer Kiana Aran makes new tools. Recently, she developed a new type of brain-on-a-chip to answer questions about the blood brain barrier.