neurological diseases

Researchers around the world are on a mission to bank biological samples from millions of people. So far, these efforts have disclosed the effects of arsenic exposure on the genome, supported development of early cancer diagnostics, and even revealed the ideal timing for COVID-19 boosters.

Many potential treatments for Alzheimer’s disease have been found using mouse models, but they often don’t translate well to humans. Will organoids provide the answers that neuroscientists need to develop new treatments?

Entomologists and computer engineers developed a novel imaging method for analyzing gene expression in live brains.

Mitochondria fragment and fuse to meet the energetic needs of the cell. Research shows that poorly regulated mitochondrial dynamics contribute to conditions such as autism.

While the blood-brain barrier is a significant obstacle to gene therapy, directed evolution of viral capsids helps ferry viral vectors across it.

Mitochondria aren’t just the bean-shaped powerhouses of the cell. They are dynamic organelles that modify their structures to match their functions. Now, new research shows that mitochondrial morphology correlates not only with function, but also with symptom severity in autism.

Mitochondria are dynamic organelles that change their morphology in response to the energetic needs of the cell. But in some disorders such as autism spectrum disorder, mitochondria don't appropriately respond, and the resulting metabolic dysfunction contributes to symptom severity.

When a research question can’t be answered using the tools available, bioengineer Kiana Aran makes new tools. Recently, she developed a new type of brain-on-a-chip to answer questions about the blood brain barrier.

New discoveries suggest it is on par with therapeutics and speeds the process of recovery and adoption of personalized treatment

Four compounds show promise against Alzheimer’s