A gene therapy hope for halting Huntington’s disease
A one-time gene therapy aims to stop Huntington's disease at its source. But first, it has to survive clinical trials.
neurodegenerative disease
A rare genetic mutation protects against Alzheimer’s disease
Data from a highly resilient individual guided researchers to new potential therapeutic targets.
Adaptive brain stimulation administers automated on-demand therapy
A new form of brain stimulation treatment that responds to a patient’s brain activity could be life changing for people with neurological and psychiatric disorders.
Exercise mimicking drugs boost brain health
Exercise-induced molecules may inspire the next generation of neuroprotective drugs.
Patient cells and serum create better Alzheimer’s disease models
Many potential treatments for Alzheimer’s disease have been found using mouse models, but they often don’t translate well to humans. Will organoids provide the answers that neuroscientists need to develop new treatments?
From Honeybees to Humans: Imaging gene expression in the brain
Entomologists and computer engineers developed a novel imaging method for analyzing gene expression in live brains.
Biotech start-ups and condensate targeted drugs
Membraneless droplet like organelles known as condensates are changing the way some scientists approach drug discovery.
Traveling to new frontiers: Antibody therapy for neurodegenerative diseases
Scientists leverage the natural ability of antibodies to cross the blood-brain barrier and target proteins implicated in neurodegenerative disease.
AI finds new uses for old drugs
Researchers built a framework to purposefully identify drug candidates for repurposing.
A shark antibody shuttles neuroprotection across the blood brain barrier
By fusing a brain-targeted antibody with an antibody that protects neurons from degeneration, scientists developed a new class of drugs that can traverse the blood brain barrier, enabling potential new treatments for Parkinson’s disease, Alzheimer’s disease, and depression.
