Channeling immune cells from the skull to the brain
Scientists imaged new communication pathways between the skull and the brain and uncovered immune responses exclusive to the skull.
neurodegeneration
Tracing Alzheimer’s disease back to development
By watching brain organoids develop, researchers observed surprising abnormalities caused by mutations in a gene related to early-onset Alzheimer’s disease.
Engineering 3D brain models
Brain organoids serve as avatars for studying human neurobiology and advancing drug discovery for neurological disorders.
Predictive and prognostic biomarker discovery for brain disorders
Slight modifications to glycoproteins reveal critical insights into disease onset, state, and progression, making them a wellspring for biomarker discovery.
Helping the brain stop neurodegeneration
A small molecule called ALGERNON2 improved health outcomes in mouse models of neurodegenerative diseases by activating antioxidant pathways in astrocytes.
Hope for prion diseases
From reducing prion protein to fighting neuroinflammation, researchers try different techniques to combat deadly prion diseases.
A gene therapy hope for halting Huntington’s disease
A one-time gene therapy aims to stop Huntington's disease at its source. But first, it has to survive clinical trials.
A rare genetic mutation protects against Alzheimer’s disease
Data from a highly resilient individual guided researchers to new potential therapeutic targets.
Adaptive brain stimulation administers automated on-demand therapy
A new form of brain stimulation treatment that responds to a patient’s brain activity could be life changing for people with neurological and psychiatric disorders.
RNA Editing in Brain Health and Disease
Scientists unravel the complexity of RNA editing to gain insights into neurodevelopmental processes and disorders.
