mitochondria

Kan Cao studies the rare aging disorder progeria to find a cure, and she’s ready to solve the mysteries of healthy human aging along the way.

Researchers discovered that copper induces cytotoxicity through a distinct pathway termed cuproptosis. This insight guides the use of copper-shuttling drugs to treat copper regulation disorders and opens up new therapeutic applications for cancer.

Armed with beautiful microscope images and new translational assays, Dylan Burnette hopes to discover novel and affordable treatments for heart disease.

Wolfram Syndrome is a rare disease that causes a myriad of challenges, including deafness, diabetes, and depression. New research suggests that an agonist used to treat neurodegenerative disorders may help alleviate some of the symptoms.

Mitochondria fragment and fuse to meet the energetic needs of the cell. Research shows that poorly regulated mitochondrial dynamics contribute to conditions such as autism.

Exercise may improve cellular power plants gone haywire to ward off Parkinson’s disease. But researchers are still trying to understand how.

Mitochondria aren’t just the bean-shaped powerhouses of the cell. They are dynamic organelles that modify their structures to match their functions. Now, new research shows that mitochondrial morphology correlates not only with function, but also with symptom severity in autism.

Mitochondria are dynamic organelles that change their morphology in response to the energetic needs of the cell. But in some disorders such as autism spectrum disorder, mitochondria don't appropriately respond, and the resulting metabolic dysfunction contributes to symptom severity.

Recent advancements in mitochondrial genome editing technologies take scientists one step closer to developing viable treatments for mitochondrial diseases, which affect 1 in 4300 adults.