microscopy

A new imaging-guided sample preparation approach enables unbiased identification of all proteins within precisely defined tissue regions, expanding opportunities for drug discovery.

Scientists developed an unprecedented chemical tool to visualize sphingomyelin and sphingomyelinase activity during a chlamydia infection.

A dementia-associated tau mutation promotes unusual clustering of Fyn, a protein important for learning and memory.

Scientists employ optogenetic tools to understand how the brain recovers from damage and generates sensory experiences.

With videos of dramatic cancer cell deaths and unflagging T cell attacks, Alex Ritter studies how immune cells and tumors battle with microscopic precision.

Armed with beautiful microscope images and new translational assays, Dylan Burnette hopes to discover novel and affordable treatments for heart disease.

Mitochondria fragment and fuse to meet the energetic needs of the cell. Research shows that poorly regulated mitochondrial dynamics contribute to conditions such as autism.

Mitochondria aren’t just the bean-shaped powerhouses of the cell. They are dynamic organelles that modify their structures to match their functions. Now, new research shows that mitochondrial morphology correlates not only with function, but also with symptom severity in autism.

Mitochondria are dynamic organelles that change their morphology in response to the energetic needs of the cell. But in some disorders such as autism spectrum disorder, mitochondria don't appropriately respond, and the resulting metabolic dysfunction contributes to symptom severity.