lungs

N-cadherins in smooth muscle cells play an important role in constricting bronchi, but inhibiting the protein could provide relief to patients with asthma.

Michael Bollong and his team discovered a way to restore lung stem cells’ regenerative capacity and a potential drug for idiopathic pulmonary fibrosis.

Injecting lung stem cells into the bloodstream of mice with idiopathic pulmonary fibrosis improved their lung function, setting the stage for human trials.

Inhibiting an enzyme variant that contributes to severe COVID-19 in men holds promise for treating SARS-CoV-2 infections. 

Denise Kirschner developed an equation-based lung model of a fatal but forgotten infectious disease, revealing an unexpected role for math in drug discovery.

Phenotypic screening may offer an alternative to traditional drug discovery.

People with cystic fibrosis seem resistant to COVID-19. Researchers developed a culture system to interrogate the mechanism behind it.