kidney disease

Inhibitors that target gut microbial enzymes are likely the key to treating a variety of cardiovascular diseases, some of which have no other cure.

A collaboration of nephrologists and biochemists created the first structure of “megalin,” a critical protein in kidney and brain disorders.

Scientists identified a DNA repair gene that may hold the key to treating chronic kidney disease.

Findings showed that Previse could predict the onset of AKI up to 48 hours in advance of onset, sooner than the standard hospital systems like XGBoost AKI prediction model and the Sequential Organ Failure Assessment (SOFA).

CKD is a slow and progressive loss of kidney function over several years, which can eventually cause permanent kidney failure. CKD often goes undetected and undiagnosed until the disease is well advanced, and the damage is irreversible resulting in poor survival rates. There are estimated to be 700 million cases of CKD worldwide, and currently there is no cure.

With a focus on comprehensive molecular disease classification, combined with prospective clinical outcomes, Chinook has the opportunity to potentially deliver targeted therapies to the right patient populations,” he added.

A look at some of the latest renal and hepatic R&D

ABIONYX achieves positive clinical results with CER-001 in familial lecithin–cholesterol acyltransferase deficiency

Eurofins Viracor and Cleveland Clinic sign licensing agreement for exclusive rights to biomarker test for detecting kidney transplant rejection

The partners' work will focus on biomarker analysis to support clinical development of RGLS4326