As reports of disrupted menstrual cycles after COVID-19 vaccinations rose, researchers investigated the connection. Their reports revealed that while vaccine-associated menstrual changes may be small and temporary, knowledge of these potential side effects is vital for public trust.
Unlike other cells in the body that mount a strong immune response against microbial invaders, skin cells use an epigenetic mechanism to ignore most of the microbes they see. These findings reveal a potential new drug target for inflammatory skin diseases.
Researchers originally believed that macrophages existed in only pro- and anti-inflammatory varieties. Over time, it became clear that many different macrophage types and subtypes exist in physiological and pathological situations. Macrophage heterogeneity brings incredible diversity to the purpose and function of these remarkable cells, but also complicates understanding how macrophages affect health and disease.