inflammation

New data suggest that an alternative mode of action may be at play for NSAIDs

T cells that react to a Parkinson’s disease-linked protein have an early, unique, and detectable gene signature.

Re-engineering immune cells helps reverse immune dysregulation associated with autoimmune diseases.

As reports of disrupted menstrual cycles after COVID-19 vaccinations rose, researchers investigated the connection. Their reports revealed that while vaccine-associated menstrual changes may be small and temporary, knowledge of these potential side effects is vital for public trust.

LIVE October 12th, 2021 at 11:30 AM ET

Bill Thelin will discuss how intestine-on-a chip technology reliably models gastrointestinal disease and assists researchers in screening for safe, effective therapeutic candidates.

Unlike other cells in the body that mount a strong immune response against microbial invaders, skin cells use an epigenetic mechanism to ignore most of the microbes they see. These findings reveal a potential new drug target for inflammatory skin diseases.

From microgravity to radiation, space wreaks havoc on astronauts’ immune systems, potentially putting them at risk of infection from microbes onboard.

Researchers originally believed that macrophages existed in only pro- and anti-inflammatory varieties. Over time, it became clear that many different macrophage types and subtypes exist in physiological and pathological situations. Macrophage heterogeneity brings incredible diversity to the purpose and function of these remarkable cells, but also complicates understanding how macrophages affect health and disease.

Exercising lab-grown human muscle can block the effects of interferon gamma