epigenetics

Two mutations in the BRCA1 gene greatly increase the risk of breast cancer. Now, it seems that only one mutation can help cells tip toward a cancerous edge. ​

No pharmaceutical treatments exist for addictions to drugs like cocaine or cannabis. Now, scientists are engineering gene therapies, immunotherapies, and more.

Lifestyle and genetics intertwine to shape individual risk and the pathway to prediabetes reversal.

Young blood rejuvenates aging organs in rodents. Researchers are studying the potential to use young blood-based treatments in aging humans too.

Negative childhood experiences can leave epigenetic scars that haunt organisms for life.

A clearer look at chromatin structures in super resolution reveals new insights into cancer pathogenesis.

With a high mortality rate and no treatment, alcoholic hepatitis is a tragic diagnosis. But a new molecule that alters patient epigenetics may become the first effective therapy for the disease.

Epigenetic events shape cancer initiation and progression. By targeting mechanisms involved in epigenetic regulation, epigenetic therapeutics serve as effective weapons against cancer.

Epigenetic therapies revive the immune cell offensive in immunotherapy resistant tumors.

Usually expressed only in the testis, FOXR2 has abnormally high expression in a variety of cancers.