drug resistance

Structural analysis of the herpes simplex virus polymerase revealed that mutations affecting its drug binding and flexibility may drive treatment resistance.

Plectasin forms dense structures on bacterial membranes by binding to unique lipids in bacterial cell walls.

Biofilms render most antibiotics ineffective, but ultrasound may be the key to clearing these chronic infections.

Organic molecules with novel biological properties offer new ways to eliminate multidrug-resistant bacteria. 

Could the solution to antibiotic resistance already have been discovered? Microbiologists and historians probe medieval and ancient texts to find out.

Insect wings contain micropillars that kill harmful microbes. Researchers designed a similar titanium surface to prevent fungal infections on medical devices.

Fully synthetic approaches expand the repertoire of possible antimicrobials to overcome existing antibiotic resistance mechanisms.

The physical arrangement of cells within a biofilm significantly influences bacteria’s access to nutrients and may affect antibiotic susceptibility.

One of the most common bacterial infections, urinary tract infections, may have promising new therapeutics on the way.

Many species of amoebae naturally bust open biofilms to eat the bacteria inside. Now, scientists are mining these microbial predators for new antibiotics.